To get you started here is a very simple script that will load an example SBML model and run a time course simulation and plot the results.

import roadrunner

# load an SBML model
rr = roadrunner.RoadRunner("mymodel.xml")

# simulate from 0 to 10 time units with 100 output rows
result = rr.simulate(0,10,100)


Looking for a model to start with? We included a couple with libRoadRunner, see Loading Models.